rRNA transcription is regulated by sequestering LATS2 and PHF6 to the nuclear speckle following DNA damage
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Mammalian large tumor suppressor 2 (LATS2) is an evolutionarily conserved Ser/Thr kinase that regulates the Hippo signaling pathway and cell cycle checkpoints. In this study, we demonstrate that ultraviolet (UV) irradiation causes the phosphorylation of LATS2 ... ...