A Minimal Four-Enzyme Suite Enables Biosynthesis of the C20 Diterpenoid Alkaloid Atisinium
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Diterpenoid alkaloids (DAs) are pharmaceutically important metabolites and mainly occur in the Ranunculaceae. Despite their structural complexity, all DAs originate from C20 diterpenoid scaffolds, making the elucidation of C20-DA biosynthesis pivotal for under... ...