Structural basis for dual targeting of μ-opioid and nociceptin/orphanin FQ receptors by Cebranopadol
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Cebranopadol is a first-in-class analgesic that combines agonism at the μ-opioid receptor (μOR) and the nociceptin/orphanin FQ receptor (NOPR), an approach proposed to improve the therapeutic index of opioid analgesia. Although Cebranopadol is highly potent ... ...
