Targeting 15-PGDH/15-oxoETE to mitigate inflammation and senescence in asthma
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Asthma is a chronic airway disease characterized by airway inflammation and remodeling. While 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and its metabolic product 15-oxo-5Z,8Z,11Z,13E-eicosatetraenoic acid (15-oxoETE), are known to participate in inflamma... ...