Phytochemicals remodel antitumor immunity via the "microbiota-metabolite-receptor" axis: focus on colorectal cancer and immunotherapy
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Colorectal cancer (CRC) is a malignancy with high mortality. Due to the suppressive state of the tumor immune microenvironment (TIME), approximately 95% of microsatellite-stable (MSS) or proficient mismatch repair (pMMR) cases exhibit poor responsiveness to im... ...