Tunable, High-Relaxivity Gd(III)-Conjugated Lipoic Acid Hydrogels for Magnetic Resonance Imaging
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A lipoic acid(LA)-base hydrogel polymerization, viscosity, and relaxivity were explored by varying several different bases, additives, Gd3+ chelates, and with or without a reducing agent (tris(2-carboxyethyl)phosphine, TCEP). The polymerization of LA was great... ...