Lewis Acid-Catalyzed Chemoselective Reduction of β,γ-Unsaturated-α-Keto Esters with Hantzsch's Ester
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We investigated chemoselective reduction of β,γ-unsaturated α-keto esters with Hantzsch ester in the presence of various Lewis acids. Among conditions surveyed for reduction with Hantzsch ester, stoichiometric TiCl4 (1.05 equiv) provided various keto esters... ...