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PrPC modulates BACE1-dependent amyloid pathology under chronic cerebral hypoperfusion: Implications for vascular cognitive impairment

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Vascular cognitive impairment (VCI) currently lacks effective pharmacological interventions, underscoring the need to identify novel therapeutic targets. Increasing evidence suggests that amyloid-β (Aβ) contributes to VCI pathogenesis by promoting neurovascu... ...