Different Roles of Canine Cytochrome P450 2C and 3A Enzymes Involved in the Oxidative Metabolism of Phenobarbital, a Key Anticonvulsant for Dogs: Comparison With Human P450 Enzymes
{{output}}
Phenobarbital is a key anticonvulsant used in dogs. Cytochrome P450 (P450) 2C19 is reportedly involved in the oxidative metabolism of phenobarbital in humans; however, the hepatic P450 enzymes responsible for phenobarbital p-hydroxylation in dogs have not yet ... ...
