Restoration of oxidative stress by HNF4α deletion in VWA8-null hepatocytes
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VWA8 is a mitochondrial protein expressed at high levels in mitochondria-enriched organs such as the liver, kidney, and heart. Deletion of VWA8 (VWA8-KO) in AML12 mouse hepatocytes leads to oxidative stress characterized by elevated production of reactive oxyg... ...
