In silico cardiac safety assessment using a multi-biomarker approach based on an electrophysiological model of hiPSC-derived cardiomyocytes
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Torsade de Pointes (TdP) is a potentially fatal ventricular arrhythmia associated with drug-induced disturbances of cardiac repolarization. Because QT interval prolongation alone provides limited mechanistic specificity, the Comprehensive in vitro Proarrhythmi... ...
