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Loss of ptr-6 restores eggshell integrity and embryonic viability in C. elegans fatty acid synthase mutants

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Fatty acid synthase (FASN) is a key rate-limited, dimeric multi-enzyme complex in the de novo lipogenesis pathway. Each FASN monomer contains seven catalytic domains, which coordinate the stepwise conversion of acetyl-CoA into fatty acids. While FASN has been ... ...