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Telomerase as a therapeutic Bullseye: advances in cancer treatment and clinical trials : A comprehensive review of small molecule inhibitors, antisense oligonucleotides, and immunotherapeutic strategies targeting the telomerase catalytic subunit (hTERT)

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Telomeres play a crucial role in maintaining genomic stability in healthy cells. However, they gradually shorten during the cell cycle, leading to chromosomal instability. Telomere length and telomerase activity are vital factors that counteract cellular degra... ...