首页 正文

Structural and evolutionary divergence of the RAG1/1L N-terminal zinc-coordinating domain

{{output}}
RAG1/2 catalyzes V(D)J recombination to assemble antigen receptor genes, but the RAG1 N-terminal zinc-coordinating domain (NZD) has remained structurally and functionally uncharacterized. Here, we determine the NMR structure of mouse RAG1 NZD, revealing a comp... ...