Dissociation of CCDC25 dimer into NETs-DNA-bound monomer licenses inflammatory activation of fibroblast-like synoviocytes in rheumatoid arthritis
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Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovium infiltration of immune cells, leading to inflammatory activation of fibroblast-like synoviocyte (FLS). Neutrophils infiltrate the synovium early in RA and exacerbate disease by... ...
