Structure-guided design of a PCSK9 epitope vaccine with efficacy against hyperlipidemia and atherosclerosis
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Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a central role in regulating low-density lipoprotein cholesterol (LDL-C) levels and has emerged as an attractive target for atherosclerotic cardiovascular disease (ASCVD) therapy. While mono-clonal an... ...
