The gut microbial lauroyl tryptamine antagonizes oxysterol-GPR183 signaling to modulate lipid-sensitive metabolic pathways in a sex-dependent manner
{{output}}
Objectives: GPR183, a G protein-coupled receptor activated by oxysterols, regulates immune and metabolic signaling in a sex-dependent manner. Lauroyl tryptamine (LT), a lipid-modified microbial metabolite, was recently identified... ...
