Molecular characterization and correlation with β-lactam resistance of penicillin-binding protein2x, 2b, and 1a of Streptococcus pneumoniae in clinical pneumococcal isolates
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Transpeptidases (TPDs), which belong to the penicillin-binding protein (PBP) families, are crucial for bacterial survival and are targeted by β-lactam antibiotics. We sought to determine the prevalence and positions of substitutions across the TPDs of the PBP... ...
