[Reducing jet lag by "softening" the circadian clock: a study using transgenic rats expressing BMAL1-dominant negative proteins in the nervous system]
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The circadian clock is an endogenous oscillator with a period of approximately 24 hours, with the central pacemaker localized in the suprachiasmatic nucleus (SCN). Jet lag occurs because the clock requires several days to entrain to a new environment. To addre... ...