HDAC10 promotes Th17 differentiation and IL-17A-driven neutrophilic airway inflammation in severe asthma
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Severe asthma frequently manifests as a neutrophilic phenotype associated with dysregulated Th17 cell response, yet the molecular mechanism regulating Th17 cell-driven pathology remain poorly defined. Here, we identified histone deacetylase (HDAC) 10 as a crit... ...