Dual repression modes triggered by constitutively stabilized beta-catenin in the dorsal neural tube underlie cell fate alterations of the roof plate, neural crest, and dorsal interneurons
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The roof plate that covers the dorsal neural tube is a key organizer or signaling center that generates morphogenetic signaling proteins to regulate neural crest cell production and dorsal CNS patterning. However, knowledge remains limited regarding the molecu... ...
