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Iodine-125 seed induces ferroptosis through inhibiting RNF216-mediated ubiquitination of p53 in cholangiocarcinoma cells

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Iodine-125 (125I) seed has effectively treated cholangiocarcinoma (CCA) in previous research. Ferroptosis, a new form of programmed cell death, is linked to cancers including CCA. However, the relationship between 125I seed and ferroptosis in CCA requires furt... ...