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Novel patient-derived tongue squamous cell carcinoma cell lines from non-smokers: 3D and in vivo models for drug response studies

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Tongue squamous cell carcinoma (TSCC) is the most prevalent and aggressive subtype of oral squamous cell carcinoma (OSCC), with a high incidence of lymph node metastasis even in early stages. The five-year overall survival rates remain low, around 50% in advan... ...