Idiopathic anaphylaxis and histamine dysregulation: Revisiting pathophysiologic assumptions
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Idiopathic anaphylaxis (IA) is a diagnosis of exclusion, and the etiology remains elusive. Research on immunoglobulin E (IgE)-mediated anaphylaxis has identified histamine as the immune system mediator, but dietary histamine's potential role in IA is often ov... ...