SHIP Blocks (MDP+LPS)-Induced Synergy in Macrophages Independent of Catalytic Activity
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Macrophages coordinate cytokine responses by integrating signals from pattern recognition receptors including NOD2 and TLR4. NOD2 detects muramyl dipeptide derived from bacterial peptidoglycan, and TLR4 recognizes lipopolysaccharide in the outer membrane of Gr... ...
