Conformational dynamics of pneumococcal polysaccharide conjugates drive UV-vis quantification errors and a strategy to enable UV-vis spectrophotometer quantification
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Accurate quantification of polysaccharide content is indispensable for the development and quality control of glycoconjugate vaccines. Conventional methods are often laborious, require large sample volumes, or are susceptible to interference. Ultraviolet-visib... ...