The TNRC6B/circTNRC6B axis drives lymphovascular invasion and metastasis through an intragenic self-degradation loop
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Lymphovascular invasion (LVI) is a critical early step in metastasis, yet the mechanisms remain elusive. We identify an intragenic antagonistic loop between TNRC6B and circTNRC6B that determines LVI and metastasis in esophageal squamous cell carcinoma. This an... ...
