PIKfyve influences inter-organelle contacts with lysosomes to modulate the endoplasmic reticulum
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Lysosomes clear unwanted cellular material delivered by constant membrane fusion. Membrane fission is thus required to balance lysosome size, number, and composition. PIKfyve is a lipid kinase that converts phosphatidylinositol-3-phosphate [PtdIns(3)P] to phos... ...
