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Unsupervised Flow Cytometry Reveals a Constant Shift Towards Activated CD4+ T Cell Subsets in APECED

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Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare monogenic autoimmune disease caused by loss-of-function mutations in the Autoimmune regulator gene and the subsequent impairment of negative selection in the thymus. Previous stu... ...