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Low fixed dose rasburicase for tumour lysis syndrome prophylaxis and treatment is feasible and efficacious in the management of haematologic malignancies

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IntroductionRasburicase is a high-cost medicine indicated for the prevention and treatment of tumour lysis syndrome (TLS). Growing evidence supports low fixed-dose rasburicase regimens (3-6 mg), however, uncertainty remains regarding their ability to prevent p... ...