In Silico Identification and Structural Characterization of High-Risk Missense SNVs in the Human IL23R Gene Relevant to Inflammatory Bowel Disease
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Background/objectives: IL23R encodes a pivotal component of the IL-23/Th17 signaling axis and represents a validated genetic susceptibility locus for inflammatory bowel disease (IBD), psoriasis, and ankylosing spondylitis. Despit... ...