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Discovery of a mutation-containing circRNA in polyglutamine disease through systematic analysis of RNAs with CAG repeats

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CAG repeat tracts occur in both non-coding and translated RNAs, have tended to lengthen throughout evolution, and are thought to enhance neuronal function. We identified over 600 human RNAs (including mRNAs, lncRNAs, and circRNAs) with at least 10 CAG repeats,... ...