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Multiscale computational evaluation of marine fungal metabolites containing iminohydantoin-like scaffolds as anti-Alzheimer drug candidates

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Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with amyloid-beta accumulation, neuroinflammation, and synaptic dysfunction, making beta-secretase 1 (BACE1) a promising therapeutic target. In the current investigation, we used ... ...