Jak1 inhibition reduces acute allodynia induced by specific upstream cytokines in rats: implications for the onset of Jak1 pain modulation
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Clinical data from patients treated with Jak1 inhibitors for diverse autoimmune diseases point to a reduction of pain at the first readouts, hinting at an action on nociceptors prior to its immunomodulatory role. Dorsal root ganglion neurons have been shown to... ...
