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Impaired BCAA Catabolism in Macrophages Exacerbates Sepsis-Induced Lung Injury by Modulating Mitochondrial AGE-RAGE and mtDNA Release

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Although macrophage immunometabolism is a key contributor to the progression of sepsis-induced acute lung injury, the specific role of branched-chain amino acid (BCAA) catabolism in this process remains unclear. Here, we hypothesized that defective BCAA catabo... ...