The novel biguanide SD282 suppresses autoimmune rheumatoid arthritis by controlling the Th17/Treg balance and restoring mitochondrial homeostasis via STAT3 regulation
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Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease driven by dysregulated Th17 cell responses and osteoclastogenesis. While metformin has shown potential in autoimmune modulation, its efficacy is often limited ... ...
