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Jaboticaba peel extract limits castration-resistant prostate cancer aggressiveness by counteracting EMT through steroid hormone and TGF-β signaling modulation

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Androgen deprivation therapy (ADT) is recommended for treating prostate cancer (PCa) that relapses after first-line approaches. However, tumors often evolve to a highly aggressive and metastatic castration-resistant phenotype (CRPC). Epithelial-to-mesenchymal ... ...