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Activin signaling inhibitor Sotatercept in pulmonary veno-occlusive disease: building a bridge to transplantation?

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Background: Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary arterial hypertension (PAH). Its prognosis is considerably worse and no medical treatment has a proven efficacy. Vasodilating drugs for PAH may contr... ...