Inhibition of FGFR signaling attenuates phosphaturia and early kidney injury in sickle cell disease mice
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We examined whether short term treatment with the pan-FGF Receptor (FGFR) inhibitor BGJ398 (Infigratinib) modulated impaired FGFR downstream signaling, phosphate wasting and markers of kidney damage in sickle cell disease (SCD) mice. Healthy control (Ctrl) and... ...
