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De novo production of (-)-limonene, (-)-carveol and (-)-carvone via engineering Rhodotorula toruloides

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De novo biosynthesis of (-)-limonene, (-)-carveol and (-)-carvone was achieved via rewiring the mevalonate pathway in the oleaginous yeast Rhodotorula toruloides. Strategies including enzyme selection, protein fusion, pathway optimization (MVA upstream enhance... ...