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Acanthamoeba profilin as a novel airway allergen with diverse sensitization patterns including pollen cross-reactivity

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Profilins are ubiquitous pan-allergens responsible for cross-reactivity between pollens and plant foods. While we previously demonstrated that recombinant Acanthamoeba profilin (rAc-PF) drives allergic airway inflammation via Th2/Th17 pathways in murine models... ...