Cancer-associated fibroblasts as a target in head and neck squamous cell carcinoma: bridging mechanisms to therapy with drugs, adjuvants, and nanotechnology
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The tumor microenvironment (TME) in head and neck squamous cell carcinoma (HNSCC) comprises a heterogeneous cellular landscape in which cancer cells, stromal cells, immune cells, and their secreted mediators collectively sustain a dynamic ecosystem. Cancer-ass... ...