Acetylation-dependent regulation of FOX-Ku interaction by GCN5-SIRT1 axis controls non-homologous end-joining DNA repair
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DNA double-strand breaks (DSBs) represent a major threat to genomic integrity. DSBs are primarily repaired through homologous recombination (HR) and non-homologous end-joining (NHEJ). The Ku complex, composed of XRCC5 and XRCC6, initiates NHEJ by binding to th... ...
