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SMN haploinsufficiency exacerbates high glucose dialysate-induced peritoneal inflammation and fibrosis via mTOR/NFκB signaling pathway

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Peritoneal dialysis (PD) is a renal replacement therapy for patients with end-stage renal disease (ESRD). However, long-term PD treatment frequently triggers peritoneal inflammation and mesothelial-to-mesenchymal (MMT), ultimately leading to irreversible perit... ...