Induced pluripotent stem cell-derived dendritic cells potentiate the efficacy of interleukin-12-expressing oncolytic HSV-1
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Oncolytic herpes simplex virus type 1 (HSV-1), including marketing-approved G47Δ, elicits antitumor immunity via facilitating antigen presentation during immune-mediated clearance of infected tumor cells. Dendritic cell (DC) therapy should therefore enhance o... ...