Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis of Tropheryma whipplei by plasma microbial cell-free DNA
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Tropheryma whipplei was identified by plasma microbial cell-free DNA sequencing within 4 days in severe culture-negative endocarditis after antibiotics had already been started. The result supported earlier diagnostic clarification and antimicrobial de-escalat... ...