Cell-autonomous co-stimulatory function of membrane-bound CD100 promotes activation and differentiation of HBcAg-specific CD8+ T cells
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Background: CD100/SEMA4D functions as a critical co-stimulatory molecule in T cell responses, existing in both membrane-bound (mCD100) and soluble (sCD100) forms. Previous studies have shown that CD100 enhances CD8+ T cell respon... ...