Chronic hypoxia protects the mouse heart from oxidative stress via HIF-1α-mitochondria crosstalk
{{output}}
Adaptation to chronic hypoxia (CH) enhances myocardial tolerance to ischemia/reperfusion injury and is closely associated with stabilization of hypoxia-inducible factor-1 alpha (HIF-1α), a central transcription factor in hypoxic response. Given the central ro... ...