Fe3+-responsive Aggregable Gold Nanoplatform Enables siRNA-Mediated Chemoresistance Reversal and Combined Photothermal-Temozolomide Therapy for Glioblastoma
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Glioblastoma (GBM) remains highly lethal, and standard temozolomide (TMZ) therapy is undermined by O6-methylguanine-DNA-methyltransferase (MGMT)-driven resistance. Herein, we present a Fe3+-responsive aggregable gold nanoplatform (siMGMT@P-T D-Q Au NP) for sys... ...
