The human adenosine A2A receptor co-isolates with anionic phospholipids in SMALPs from Pichia pastoris membranes
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The adenosine A2A receptor (A2AR) is a GPCR that binds adenosine, leading to modulation of inflammation, platelet aggregation and vasodilation of coronary arteries. It is known that phospholipids surrounding GPCRs affect their activity but these effects have l... ...